Cinchona officinalis Linn. |
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Botanical Name |
: |
Cinchona officinalis Linn. |
English
Name |
: |
Peruvian, Crown or Pale Cinchona Bark |
Synonym(s) |
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Cinchona uritusinga. Cinchona condaminea. Cinchona academica. Cinchona crispa and Cinchona chahuarguera |
Family |
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Rubiaceae |
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General Info
| Description |
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A tree 6-15 m in height with rough brown bark, having pale yellow markings inside and dull white ones outside, 7-15 cm long, ovate-lanceolate leaves with reddish green petioles, red flowers in coryliform cymes, oblong, 12-20 mm long capsules and elliptic winged seeds. |
| Herb Effects |
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Antimalarial (plant and bark); antiarrhythmic and cardiotonic (plant); antipyretic, stringent and antiseptic (bark); antiparasitic, antiprotozoal, antispasmodic, bitter digestive aid, cardiotonic (tones, balances, strengthens the heart). |
Chemistry
| Active Ingredients |
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Quinine,quinidine, cinchonidine, cinchonine and cinchotannic acid(Plant); quercetin, kaempferol and avicularin (leaves) |
| Chemistry
of Active Ingredients |
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|
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Name |
CAS# |
IUPAC Name |
Formula |
Structure |
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|
| Quinine |
72646-90-3 |
(2-ethenyl-4-azabicy
clo[2.2.2]oct-5-yl)-
(6-methoxyquinolin-4
-yl)-metha
nol |
C20H24N2O2 |
|
| Quinidine |
Not Available |
(3-ethenyl-7-bicyclo
[2.2.2]octyl)-(6-met
hoxy-1H-quinolin-4-y
l)-methano
l |
C21H26NO2+ |
|
| Cinchonidine |
485-71-2 |
(2-ethenyl-4-azabicy
clo[2.2.2]oct-5-yl)-
quinolin-4-yl-methan
ol |
C19H22N2O |
|
| Cinchonine |
24831-03-6 |
(2-ethenyl-4-azabicy
clo[2.2.2]oct-5-yl)-
quinolin-4-yl-methan
ol |
C19H22N2O |
|
| Quercetin |
Not Available |
2-(3,4-dihydroxyphen
yl)-3,4,5-trihydroxy
-chromen-7-one |
C15H10O7 |
|
| Kaempferol |
80714-53-0 |
3-[3-[4,5-dihydroxy-
6-(hydroxymethyl)-3-
[3,4,5-trihydroxy-6-
(hydroxyme
thyl)oxa
n-2-yl]oxy-oxan-2-yl
]oxy-4,5-dihydroxy-6
-(hydroxymethyl)oxan
-2
-yl]oxy-4,5-dihy
droxy-2-(4-hydroxyph
enyl)-chromen-7-one |
C33H40O21 |
|
| Avicularin |
Not Available |
2-(3,4-dihydroxyphen
yl)-5,7-dihydroxy-3-
(4,5,6-trihydroxyoxa
n-3-yl)oxy
-chroman
-4-one |
C20H20O11 |
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Pharmacology
| Medicinal Use |
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As a tonic in intermittent fevers, debility, leucorrhea, smallpox, rheumatism, etc.. in skin ulcers and gum problems (bark); sore throat (bark decoction or infusion) |
| Contraindication |
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May potentiate blood thinning medications such as Warfarin.® |
| Reference |
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 Chandel et al., Biodiversity in Medicinal Aromatic Plants inIndia.
Bentley and Trimen, Medicinal Plants. |
Dealers
Products
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