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Home » Plant infomation

Allamanda cathartica  Linn.

   

click to enlarge image

Botanical Name

:

Allamanda cathartica Linn.

English Name

:

Campanilla

Synonym(s)

:

Allamanda hendersonii Bull ex Dombrain

Family

:

Apocynaceae

 

General Info

Description

An erect, evergreen, variable shrub, up to 4 m in height. Leaves whorled, obovate to oblong-lanceolate, 8-12 cm ° 2.5-4.0 cm, wavy; flowers large, showy, bright- or golden-yellow, in terminal, cymose panicles; capsules prickly; seeds many, obovate, flat, winged.

Herb Effects

Antifungal (flower); against human carcinoma cells of the nasopharynx (in vitro) and against leukemia (in vivo) (50% EtOH extract of roots).

Links

Floridata
PIER

Chemistry

Active Ingredients

Ursolic acid, beta-amyrin and beta-sitosterol (leaf); plumericin and isoplumericin (stem and root bark).

Chemistry of Active Ingredients
Product Categories

Name

CAS#

IUPAC Name

Formula

Structure

Product Categories
Ursolic acid 77-52-1 10-hydroxy-1,2,6a,6b
,9,9,12a-heptamethyl
-2,3,4,5,6,6a,7,8,8a
,10,11,12,
C30H48O3 Click Here To Enlarge
Beta-Amyrin 559-70-6 4,4,6a,6b,8a,11,11,1
4b-octamethyl-1,2,3,
4a,5,6,7,8,9,10,12,1
2a,14,14a- tetradec
ahydropicen-3-ol
C30H50O Click Here To Enlarge
Beta-Sitosterol 5779-62-4 17-(5-ethyl-6-methyl
-heptan-2-yl)-10,13-
dimethyl-2,3,4,7,8,9
,11,12,14, 15,16,17
-dodecahydro-1H-cycl
openta[a]phenanthren
-3-ol
C29H50O Click Here To Enlarge
Plumericin 77-16-7 Not Available C15H14O6 Click Here To Enlarge
Isoplumericin 31298-76-7 Not Available C15H14O6 Click Here To Enlarge

Pharmacology

Medicinal Use

In nasopharyngeal cancer and leukemia (leaf extract); as an antifungal agent (flower).

Contraindication

All parts of the plant contain the iridoid lactone allamandin and may produce symptoms of vomiting or diarhea if ingested.

Reference

Abdel-Kader MS. Wisse J. Evans R. van der Werff H. Kingston DG. Bioactive iridoids and a new lignan from Allamanda cathartica and Himatanthus fallax from the Suriname rainforest. J Nat Prod 1997 Dec;60(12):1294-7.

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