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Fritillaria thunbergii Miq.


Botanical Name	:	Fritillaria thunbergii Miq.
English Name	:	Zhejiang fritillary
Synonym(s)	:	Fritillaria collicola Hance, Fritillaria verticillata var. thunbergii (Miq.) Baker.
Family	:	Liliaceae

General Info

Description

A perennial herb. Bulb of 2 or 3 scales, ovoid or globose, 1--3 cm in diam. Stem 15--80 cm. Leaves 12-20, opposite, alternate, or sometimes also 3-whorled; leaf blade linear-lanceolate to lanceolate, 7-11 Ã— 1-2.5 cm, apex usually slightly cirrose. Inflorescence 1-6-flowered; bracts 2-4, apex cirrose. Flowers nodding, campanulate; pedicel 1-3.5 cm. Tepals pale yellow, sometimes tinged with pale purple or slightly tessellated with purplish brown, oblong-elliptic to narrowly obovate-oblong, 2.5-3.5 Ã— 1-1.8 cm; nectaries small. Stamens 1-1.5 cm; filaments glabrous. Style 3-lobed; lobes 1.5-2 mm. Capsule broadly winged; wings 6-8 mm wide.

Herb Effects

Antidote, antitussive, astringent, expectorant, galactogogue and purgative (bulb)

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Chemistry

Active Ingredients

Beta-sitosterol, campesterol, fritillarine, fritilline, stigmasterol, succinic acid, thymidine, verticilline, verticine (bulb); peimine (stem)

Chemistry of Active Ingredients

Name

CAS#

IUPAC Name

Formula

Structure

Beta-sitosterol

5779-62-4

17-(5-ethyl-6-methyl
-heptan-2-yl)-10,13-
dimethyl-2,3,4,7,8,9
,11,12,14,

C₂₉H₅₀O

Campesterol

474-62-4

17-(5,6-dimethylhept
an-2-yl)-10,13-dimet
hyl-2,3,4,7,8,9,11,1
2,14,15,16 ,17-dode
cahydro-1H-cyclopent
a[a]phenanthren-3-ol

C₂₈H₄₈O

Fritillarine

18059-10-4

Not Available

C₂₇H₄₃NO₃

Fritilline

Not Available

Stigmasterol

4736-55-4

17-(4-ethyl-1,5-dime
thyl-hex-2-enyl)-10,
13-dimethyl-1,2,4,5,
6,7,8,9,10
,11,12,13,14,15,16,1
7-hexadecahydrocyclo
penta[a]phenanthren-
3-one

C₂₉H₄₈O

Succinic acid

6283-68-7

butanedioic acid

C₄H₆O₄

Thymidine

Not Available

1-[(2R,4S,5R)-4-hydr
oxy-5-(hydroxymethyl
)oxolan-2-yl]-5-meth
yl-pyrimid ine-2,4-
dione

C₁₀H₁₄N₂O₅

Verticilline

Not Available

Verticine

23496-41-5

Not Available

C₂₇H₄₅NO₃

Peimine

23496-41-5

Not Available

C₂₇H₄₅NO₃

Pharmacology

Medicinal Use

The bulbs are thought to act specifically on tumours and swellings of the throat, neck and chest, and they are taken in the treatment of thyroid gland nodules, scrofula, abscesses and boils and breast cancer. The bulb is used internally in the treatment of coughs, bronchitis, pneumonia, feverish illnesses, abscesses etc. and used against cancer in folk medicine.

Contraindication

Should be used under the supervision of a qualified practitioner, excessive doses can cause breathing difficulties and heart failure.

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